| Property |
Value |
| Working Groups |
RG Kusch, 
RG Mager, 
RG Moser, 
RG Wolf |
| Subproject |
A04, B01 |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
41366521 |
| DOI |
10.1038/s44321-025-00350-z |
| Publication Year |
2025 |
| Title |
Channelrhodopsin variants for high-rate optogenetic neurostimulation at low light intensities |
| Journal |
EMBO Molecular Medicine |
| ISSN |
1757-4676 |
| eISSN |
1757-4684 |
| URL |
https://doi.org/10.1038/s44321-025-00350-z |
| Journal Abbreviation |
EMBO Mol Med |
| Authors |
Roos L, Garrido-Charles A, Albrecht N, Vavakou A, Alekseev A, Bleyer M, Thirumalai A, Mittring A, Alvanos T, Huet AT, Bamberg E, Kusch K, Wolf BJ, Moser T, Mager T |
| First Author |
Roos L |
| Last Author |
Mager T |
External Resources
link.spr...-z.pdfhttps://link.springer.com/content/pdf/10.1038/s44321-025-00350-z.pdf Article fulltext
2/153376https://publications.goettingen-research-online.de/handle/2/153376 GRO.publications identifier
ebi.ac.u...0350-zhttps://www.ebi.ac.uk/biostudies/studies/https://www.ebi.ac.uk/biostudies/studies/S-SCDT-10_1038-S44321-025-00350-z EMBL-EBI biostudies identifier (S-SCDT-10_1038-S44321-025-00350-z)
AF461397https://www.ncbi.nlm.nih.gov/nuccore/AF461397 NCBI nucleotide (AF461397, reused)
KF992040https://www.ncbi.nlm.nih.gov/nuccore/KF992040 NCBI nucleotide (KF992040, reused)
10047https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10047 NCBI taxonomy (Mongolian gerbil, Meriones unguiculatus)
10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 NCBI taxonomy (mouse, Mus musculus)
10116https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10116 NCBI taxonomy (rat, Rattus norvegicus)
0009-0007-8051-7964https://orcid.org/0009-0007-8051-7964 ORCID identifier (Lennart Roos)
0000-0002-9577-6682https://orcid.org/0000-0002-9577-6682 ORCID identifier (Aida Garrido Charles)
0009-0004-5243-5097https://orcid.org/0009-0004-5243-5097 ORCID identifier (Niels Albrecht)
0000-0003-2812-4999https://orcid.org/0000-0003-2812-4999 ORCID identifier (Anna Vavakou)
0000-0001-8990-1662https://orcid.org/0000-0001-8990-1662 ORCID identifier (Alexey Alekseev)
0009-0009-6409-0790https://orcid.org/0009-0009-6409-0790 ORCID identifier (Martina Bleyer)
0000-0002-3624-0343https://orcid.org/0000-0002-3624-0343 ORCID identifier (Anupriya Thirumalai)
0000-0003-2344-5136https://orcid.org/0000-0003-2344-5136 ORCID identifier (Artur Mittring)
0000-0002-0274-5642https://orcid.org/0000-0002-0274-5642 ORCID identifier (Theocharis Alvanos)
0000-0001-6151-7183https://orcid.org/0000-0001-6151-7183 ORCID identifier (Antoine Tarquin Huet)
0000-0002-5411-6207https://orcid.org/0000-0002-5411-6207 ORCID identifier (Ernst Bamberg)
0000-0002-5079-502Xhttps://orcid.org/0000-0002-5079-502X ORCID identifier (Kathrin Kusch)
0000-0003-0512-1381https://orcid.org/0000-0003-0512-1381 ORCID identifier (Bettina Julia Wolf)
0000-0001-7145-0533https://orcid.org/0000-0001-7145-0533 ORCID identifier (Tobias Moser)
0000-0002-9571-7033https://orcid.org/0000-0002-9571-7033 ORCID identifier (Thomas Mager)
17https://rdp.ekfz.uni-goettingen.de/literature/publication/17 Published Data Registry entry (EKFZ)
417https://sfb1286.uni-goettingen.de/literature/publications/417 Published Data Registry entry (CRC 1286)
1327https://prod.mbexc.uni-goettingen.de/literature/publications/1327 Published Data Registry entry (MBExC)
02f99v835https://ror.org/02f99v835 ROR identifier (02f99v835, German Primate Center)
03av75f26https://ror.org/03av75f26 ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
02panr271https://ror.org/02panr271 ROR identifier (02panr271, Max Planck Institute of Biophysics)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
CVCL_0464https://scicrunch.org/resolver/CVCL_0464 SciCrunch identifier (RRID:CVCL_0464, 108CC15)
SCR_018866https://scicrunch.org/resolver/SCR_018866 SciCrunch identifier (RRID:SCR_018866, Axopatch 200B Patch Clamp Amplifier)
SCR_018361https://scicrunch.org/resolver/SCR_018361 SciCrunch identifier (RRID:SCR_018361, Biorender)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_000325https://scicrunch.org/resolver/SCR_000325 SciCrunch identifier (RRID:SCR_000325, IGOR Pro)
SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_013673https://scicrunch.org/resolver/SCR_013673 SciCrunch identifier (RRID:SCR_013673, Leica Application Suite X)
SCR_016844https://scicrunch.org/resolver/SCR_016844 SciCrunch identifier (RRID:SCR_016844, Leica CM3050 S Research Cryostat)
SCR_018169https://scicrunch.org/resolver/SCR_018169 SciCrunch identifier (RRID:SCR_018169, Leica SP8 LIGHTNING confocal microscope)
SCR_018453https://scicrunch.org/resolver/SCR_018453 SciCrunch identifier (RRID:SCR_018453, Leica VT1200S vibratome)
SCR_001622https://scicrunch.org/resolver/SCR_001622 SciCrunch identifier (RRID:SCR_001622, MATLAB)
SCR_014212https://scicrunch.org/resolver/SCR_014212 SciCrunch identifier (RRID:SCR_014212, Origin)
SCR_000034https://scicrunch.org/resolver/SCR_000034 SciCrunch identifier (RRID:SCR_000034, Patchmaster)
SCR_011323https://scicrunch.org/resolver/SCR_011323 SciCrunch identifier (RRID:SCR_011323, pClamp)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM4_ESM.pdf Supplemental material
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM13_ESM.pdf Supplemental material (figure)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM5_ESM.pdf Supplemental material (peer review)
static-c...SM.ziphttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM6_ESM.zip Supplemental material (source data)
static-c...SM.ziphttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM7_ESM.zip Supplemental material (source data)
static-c...SM.ziphttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM8_ESM.zip Supplemental material (source data)
static-c...SM.ziphttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM9_ESM.zip Supplemental material (source data)
static-c...SM.ziphttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM10_ESM.zip Supplemental material (source data)
static-c...SM.ziphttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM11_ESM.zip Supplemental material (source data)
static-c...SM.ziphttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM12_ESM.zip Supplemental material (source data)
static-c...M.docxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM1_ESM.docx Supplemental material (table)
static-c...M.docxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM2_ESM.docx Supplemental material (table)
static-c...M.docxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-025-00350-z/MediaObjects/44321_2025_350_MOESM3_ESM.docx Supplemental material (table)
10.5281/zenodo.17458418https://doi.org/10.5281/zenodo.17458418 Zenodo identifier (10.5281/zenodo.17458418)
10.5281/zenodo.15210800https://doi.org/10.5281/zenodo.15210800 Zenodo identifier (10.5281/zenodo.15210800, reused)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0010 |
|
primary |
GFP |
AB_300798 |
Anti-GFP antibody |
| primary-0011 |
|
primary |
SLC17A7 |
AB_887878 |
Anti-VGLUT 1 antibody |
| primary-0012 |
|
primary |
HOME1 |
AB_2120990 |
Homer1 antibody |
| primary-0013 |
|
primary |
PVALB |
AB_2156476 |
Anti-Parvalbumin antibody |
| primary-0014 |
|
primary |
CALB2 |
AB_2721226 |
Calretinin antibody |
| primary-0015 |
|
primary |
ATP1A3 |
AB_531527 |
Sodium Potassium ATPase Alpha 3 Antibody (XVIF9-G10) - BSA Free |
| primary-0020 |
|
primary |
CD3 |
|
Polyclonal Rabbit Anti-Human CD3 |
| primary-0021 |
|
primary |
Iba1 |
AB_1240433 |
Iba1 antibody |
| secondary-0006 |
|
secondary |
|
AB_2534096 |
Goat anti-Chicken IgY (H+L) Secondary Antibody, Alexa Fluor 488 |
| secondary-0007 |
|
secondary |
|
AB_2535812 |
Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 647 |
| secondary-0016 |
|
secondary |
|
AB_2534119 |
Goat anti-Guinea Pig IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 568 |
| secondary-0017 |
|
secondary |
|
AB_2535731 |
Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor™ 633 |
| secondary-0018 |
|
secondary |
|
AB_2735091 |
Goat anti-Guinea Pig IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor™ 647 |
| secondary-0019 |
|
secondary |
|
AB_11180865 |
Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor™ 568 |